公开(公告)号：US20200079736A1

公开(公告)日：2020-03-12

申请号：US16684216

申请日：2019-11-14

Applicant: AMGEN INC. ,  CYTOKINETICS, INC.

Inventor： Sheng Cui ,  Henry Morrison ,  Karthik Nagapudi ,  Shawn Walker ,  Charles Bernard ,  Karl Bennett Hansen ,  Neil Fred Langille ,  Alan Martin Allgeier ,  Steven Mennen ,  Jacqueline C.S. Woo ,  Bradley Paul Morgan ,  Alex Muci

IPC: C07D213/75 ,  A61K47/38 ,  A61K31/496 ,  A61K9/20

Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.

公开(公告)号：US20200331859A1

公开(公告)日：2020-10-22

申请号：US16920155

申请日：2020-07-02

Applicant: AMGEN INC. ,  CYTOKINETICS, INC.

Inventor： Sheng Cui ,  Henry Morrison ,  Karthik Nagapudi ,  Shawn Walker ,  Charles Bernard ,  Karl Bennett Hansen ,  Neil Fred Langille ,  Alan Martin Allgeier ,  Steven Mennen ,  Jacqueline C.S. Woo ,  Bradley Paul Morgan ,  Alex Muci

IPC: C07D213/75 ,  A61K9/20 ,  A61K31/496 ,  A61K47/38

Abstract: Provided are omecamtiv mecarbil dihydrochloride salt forms, compositions and pharmaceutical formulations thereof, and methods for their preparation and use.