公开(公告)号：US11583560B2

公开(公告)日：2023-02-21

申请号：US16759892

申请日：2018-10-05

Applicant: AMOREPACIFIC CORPORATION

Inventor： Eun-Gyung Cho ,  Wanil Kim ,  Tae Ryong Lee

IPC: A61K35/747 ,  A23L33/135 ,  A61K8/14 ,  A61K8/99

Abstract: The present specification discloses an immunomodulatory composition comprising lactobacillus-derived extracellular vesicles as an active ingredient. The lactobacillus may be Lactobacillus plantarum. The composition has the effects of inducing differentiation into M2-type macrophages and reducing expression of at least one member selected from the group consisting of CCR2, SOCS3 and HLA-DRα, which are M1-type macrophage differentiation markers.