公开(公告)号：US11708594B2

公开(公告)日：2023-07-25

申请号：US16653235

申请日：2019-10-15

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Nicholas Stephanopoulos ,  Minghui Liu

IPC: C12P19/34 ,  C12N15/11 ,  B82Y40/00 ,  B82Y5/00

CPC classification number: C12P19/34 ,  C12N15/111 ,  B82Y5/00 ,  B82Y40/00 ,  C12N2310/122 ,  C12N2310/3181 ,  C12N2310/531

Abstract: A photocaged DNA nano-tweezer and methods of using said photocaged DNA nano-tweezer are described. In particular, provided herein is a DNA nano-tweezer comprising a hairpin with a single-stranded loop that comprises a first arm and a second arm; and a trigger strand complementary to the single-stranded loop and comprising at least one photocaged residue with a protecting group.

公开(公告)号：US20240011065A1

公开(公告)日：2024-01-11

申请号：US18327434

申请日：2023-06-01

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Nicholas Stephanopoulos ,  Minghui Liu

IPC: C12P19/34 ,  C12N15/11

CPC classification number: C12P19/34 ,  C12N15/111 ,  C12N2310/122 ,  B82Y40/00

Abstract: A photocaged DNA nano-tweezer and methods of using said photocaged DNA nano-tweezer are described. In particular, provided herein is a DNA nano-tweezer comprising a hairpin with a single-stranded loop that comprises a first arm and a second arm; and a trigger strand complementary to the single-stranded loop and comprising at least one photocaged residue with a protecting group.