专利检索 ap:("ASSOCIATION ISNTITUT DE MYOLOGIE" OR "INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)" OR "SORBONNE UNIVERSITE" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)") AND inv:"Delphine Trochet" 第 1 页

1.

发明授权
Allele-specific silencing therapy for dynamin 2-related diseases 有权

公开(公告)号：US11926829B2

公开(公告)日：2024-03-12

申请号：US17166377

申请日：2021-02-03

申请人： ASSOCIATION ISNTITUT DE MYOLOGIE , INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , SORBONNE UNIVERSITE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)

发明人： Marc Bitoun , Delphine Trochet , Bernard Prudhon

IPC分类号： C12N15/113

CPC分类号： C12N15/1137 , C12N2310/14 , C12N2320/34 , C12Y306/05005

摘要： The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.

2.

发明授权
Allele-specific silencing therapy for Dynamin 2-related diseases 有权

公开(公告)号：US10947540B2

公开(公告)日：2021-03-16

申请号：US16464482

申请日：2017-11-19

申请人： ASSOCIATION INSTITUT DE MYOLOGIE , INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE , SORBONNE UNIVERSITE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

发明人： Marc Bitoun , Delphine Trochet , Bernard Prudhon

IPC分类号： C12N15/113

摘要： The invention relates to an allele specific siRNA able to silence the expression of only one allele of a heterozygous DNM2 gene, for treating diseases caused by heterozygous mutation and/or overexpression of Dynamin 2.