公开(公告)号：US10280184B2

公开(公告)日：2019-05-07

申请号：US15304131

申请日：2015-04-16

申请人： AbbVie Inc.

发明人： Michael M. Friedman ,  Philip Cox ,  Kristine E. Frank ,  Michael Z. Hoemann ,  Augustine Osuma ,  Noel S. Wilson ,  Xiangdong Xu ,  Kevin Cusack ,  Raymond Huntley ,  J. Martin Herold

IPC分类号： C07D471/04 ,  C07D519/00 ,  A61K31/437 ,  C07D487/04 ,  C07D498/04

摘要： The invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.

公开(公告)号：US20190135836A1

公开(公告)日：2019-05-09

申请号：US16230408

申请日：2018-12-21

申请人： AbbVie Inc.

发明人： Michael Friedman ,  Phil Cox ,  Kristine E. Frank ,  Michael Z. Hoemann ,  Augustine Osuma ,  Noel S. Wilson ,  Xiangdong Xu ,  Kevin Cusack ,  Raymond Huntley ,  J. Martin Herold

IPC分类号： C07D519/00 ,  A61K31/437 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04

摘要： This invention provides compounds of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers, and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.