公开(公告)号：US08906911B2

公开(公告)日：2014-12-09

申请号：US13853394

申请日：2013-03-29

Applicant: AbbVie Inc.

Inventor： Michael D. Meyer ,  Xueqing Wang ,  Tao Guo ,  Robert Guo Ping Wei ,  Lijuan Jane Wang

IPC: C07D487/04 ,  C07D487/08 ,  A61K31/427 ,  A61K31/407 ,  A61K31/4439 ,  A61K31/501 ,  A61K31/506 ,  A61K31/4995 ,  A61K31/5377 ,  C07D451/02

CPC classification number: C07D487/08 ,  C07D451/02

Abstract: Disclosed herein are chemokine receptor antagonists of formula (I) wherein R1, R2, and R3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

Abstract translation: 本文公开了式（I）的趋化因子受体拮抗剂，其中R 1，R 2和R 3如说明书中所定义。 包含这些化合物的组合物; 还描述了使用这些化合物和组合物治疗病症和病症的方法。

公开(公告)号：US20130261129A1

公开(公告)日：2013-10-03

申请号：US13853394

申请日：2013-03-29

Applicant: ABBVIE INC.

Inventor： Michael D. Meyer ,  Xueqing Wang ,  Tao Guo ,  Robert Wei ,  Lijuan Jane Wang

IPC: C07D487/08 ,  C07D451/02

CPC classification number: C07D487/08 ,  C07D451/02

Abstract: Disclosed herein are chemokine receptor antagonists of formula (I) wherein R1, R2, and R3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

Abstract translation: 本文公开了式（I）的趋化因子受体拮抗剂，其中R 1，R 2和R 3如说明书中所定义。 包含这些化合物的组合物; 还描述了使用这些化合物和组合物治疗病症和病症的方法。