公开(公告)号：US20190336496A1

公开(公告)日：2019-11-07

申请号：US16277091

申请日：2019-02-15

Applicant: AbbVie Inc.

Inventor： Tamar Uziel ,  Joel D. Leverson ,  William N. Pappano ,  Dipica B. Maganbhai Haribhai ,  Rebecca Mathew ,  Fred Kohlhapp ,  Cherie K. Donawho

IPC: A61K31/496 ,  A61K31/5377 ,  C07K16/28 ,  A61P35/00

Abstract: This invention pertains to a method for the treatment of cancer in a subject comprising administering to the subject an effective amount of a selective BCL-2 inhibitor or a prodrug or pharmaceutically acceptable salt thereof in combination with an effective amount of an anti-PD-1 antibody or an anti-PD-L1 antibody.