公开(公告)号：US20240115724A1

公开(公告)日：2024-04-11

申请号：US18320869

申请日：2023-05-19

Applicant: AbbVie Inc.

Inventor： Shweta SINGH ,  Jennifer Hope RICHARDSON ,  Laura Patterson SERWER ,  Jonathan Alexander TERRETT ,  Susan E. MORGAN-LAPPE ,  Tracy HENRIQUES ,  Sherry L. RALSTON ,  Marvin Robert LEANNA ,  Ilaria BADAGNANI

IPC: A61K47/68 ,  A61P35/00 ,  C07K16/28

CPC classification number: A61K47/6849 ,  A61K47/6817 ,  A61K47/6851 ,  A61K47/6889 ,  A61P35/00 ,  C07K16/2881 ,  C07K2317/33 ,  C07K2317/77 ,  C07K2319/50

Abstract: The invention relates generally to conjugated activatable antibodies that bind CD71 in their active form and methods of making and using these anti-CD71 conjugated activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

公开(公告)号：US20190111150A1

公开(公告)日：2019-04-18

申请号：US16159559

申请日：2018-10-12

Applicant: AbbVie Inc.

Inventor： Shweta SINGH ,  Jennifer Hope RICHARDSON ,  Laura Patterson SERWER ,  Jonathan Alexander TERRETT ,  Susan E. MORGAN-LAPPE ,  Tracy HENRIQUES ,  Sherry L. RALSTON ,  Marvin Robert LEANNA ,  Ilaria BADAGNANI ,  Sahana BOSE

IPC: A61K47/68 ,  A61P35/00 ,  C07K16/28

Abstract: The invention relates generally to conjugated activatable antibodies that bind CD71 in their active form and methods of making and using these anti-CD71 conjugated activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.