-
公开(公告)号：US20210023234A1
公开(公告)日：2021-01-28
申请号：US17043082
申请日：2019-03-28
申请人： AbbVie Inc.
摘要： Disclosed herein are ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) complexes and synthetic molecules that interact with an ENPP protein. In some embodiments, also disclosed herein are modified ENPP polypeptides in complex with a synthetic molecule described herein.
-
2.发明公开公开(公告)号：US20230183239A1
公开(公告)日：2023-06-15
申请号：US17702597
申请日：2022-03-23
申请人： AbbVie Inc.
发明人： William Michael GALLATIN , Joshua ODINGO , Gregory N. DIETSCH , Vincent FLORIO , Chandregowda VENKATESHAPPA , Athisayamani Jeyaraj DURAISWAMY
IPC分类号： C07D471/10 , C07D211/28 , C07D215/233 , C07D215/44 , C07D239/88 , C07D239/94 , C07D241/42 , C07D307/81 , C07D311/22 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/12 , C07D413/14 , C07D471/04 , C07D487/04 , C07D519/00 , C07F5/02
CPC分类号： C07D471/10 , C07D211/28 , C07D215/44 , C07D215/233 , C07D239/88 , C07D239/94 , C07D241/42 , C07D307/81 , C07D311/22 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/12 , C07D413/14 , C07D471/04 , C07D487/04 , C07D519/00 , C07F5/025
摘要： Disclosed herein are methods and compounds of augmenting and enhancing the production of type I IFNs in vivo. In some embodiments, the compounds disclosed herein are ENPP-1 inhibitors, pharmaceutical compositions, and methods for the treatment of cancer or a viral infection.
-
3.发明申请公开(公告)号：US20200291024A1
公开(公告)日：2020-09-17
申请号：US16639944
申请日：2018-08-31
申请人： AbbVie Inc.
IPC分类号： C07D471/10 , C07D401/04 , C07D401/14 , C07D413/14 , C07D405/14 , C07D487/04 , C07D211/28 , C07D215/233 , C07D215/44 , C07D471/04 , C07D239/88 , C07D239/94 , C07D241/42 , C07D409/12 , C07D519/00 , C07F5/02 , C07D307/81 , C07D311/22
摘要： Disclosed herein are methods and compounds of augmenting and enhancing the production of type I IFNs in vivo. In some embodiments, the compounds disclosed herein are ENPP-1 inhibitors, pharmaceutical compositions, and methods for the treatment of cancer or a viral infection.
-
-
搜索结果
3 条记录 (耗时 0.01 秒)
