公开(公告)号：US20190105328A1

公开(公告)日：2019-04-11

申请号：US16219450

申请日：2018-12-13

申请人： AbbVie Inc. ,  AbbVie Biotherapeutics Inc.

发明人： Kurt C. GISH ,  Jonathan A. HICKSON ,  Susan Elizabeth MORGAN-LAPPE ,  James W. PURCELL

IPC分类号： A61K31/5517 ,  A61K47/68 ,  C07K16/28 ,  A61K39/395 ,  A61K38/07 ,  C07K16/30 ,  A61K39/00

摘要： The present disclosure provides antibodies, antibody binding fragments, and antibody drug conjugates that bind human LRRC15, their methods of making, and their uses to treat patients having cancer.

公开(公告)号：US20190105329A1

公开(公告)日：2019-04-11

申请号：US16219547

申请日：2018-12-13

申请人： AbbVie Inc. ,  AbbVie Biotherapeutics Inc.

发明人： Kurt C. GISH ,  Jonathan A. HICKSON ,  Susan Elizabeth MORGAN-LAPPE ,  James W. PURCELL

IPC分类号： A61K31/5517 ,  A61K47/68 ,  C07K16/28 ,  A61K39/395 ,  A61K38/07 ,  C07K16/30 ,  A61K39/00

摘要： The present disclosure provides antibodies, antibody binding fragments, and antibody drug conjugates that bind human LRRC15, their methods of making, and their uses to treat patients having cancer.

公开(公告)号：US20190099431A1

公开(公告)日：2019-04-04

申请号：US16216795

申请日：2018-12-11

申请人： AbbVie Inc. ,  AbbVie Biotherapeutics Inc.

发明人： Kurt C. GISH ,  Jonathan A. HICKSON ,  Susan Elizabeth MORGAN-LAPPE ,  James W. PURCELL

IPC分类号： A61K31/5517 ,  A61K47/68 ,  A61K38/07 ,  C07K16/30 ,  C07K16/28

摘要： The present disclosure provides antibodies, antibody binding fragments, and antibody drug conjugates that bind human LRRC15, their methods of making, and their uses to treat patients having cancer.