公开(公告)号：US08657447B2

公开(公告)日：2014-02-25

申请号：US13755295

申请日：2013-01-31

Applicant: Abbott Medical Optics Inc.

Inventor： Stanley W Huth ,  Denise Tran

IPC: A61B3/00

CPC classification number: A61B3/101

Abstract: Methods and devices measure eye blinks and tear film lipid and aqueous layer thickness before and following ophthalmic formula application onto the ocular surface, especially wherein the ophthalmic formula is an artificial tear. The methods and devices are suitable for dry eye diagnosis. The methods and devices are suitable for use to evaluate ophthalmic formula effects on the tear film and to use such information to diagnose ophthalmic formula treatment of ocular disease conditions such as dry eye in the absence of contact lens wear or post-surgical eye drop treatment and diagnosis. The methods and devices are also suitable for use in the optimization of ophthalmic drug dosage forms and sustained drug release.

Abstract translation: 方法和装置测量眼用配方之前和之后的眼睛眨眼和撕裂膜脂质和水层厚度，特别是其中眼用配方是人造眼泪。 该方法和装置适用于干眼诊断。 所述方法和装置适合用于评估眼用配方对泪液膜的影响，并使用此类信息来诊断在没有接触镜磨损或手术后滴眼治疗的情况下眼部疾病状况如眼睛眼病的眼科配方治疗，以及 诊断。 所述方法和装置也适用于优化眼药物剂型和持续的药物释放。