专利检索 ap:("Acerta Pharma B.V.") AND inv:"Michael David GOLDEN" 第 1 页

1.

发明申请
PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-a]-PYRAZIN-1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE 有权

公开(公告)号：US20220127270A1

公开(公告)日：2022-04-28

申请号：US17271750

申请日：2019-08-28

申请人： Acerta Pharma B.V.

发明人： Paul Allen BETHEL , Lai Chun CHAN , Katie Grace COOPER , Robert John COX , Michael David GOLDEN , Shaun Alan HUGHES , Lucinda Victoria JACKSON , Kirsty Jane MILLARD , Andrew John PHILLIPS , Alexander James TELFORD , Jerry EVARTS , Michael Joseph LAWLER , Remy E. J. N. LITJENS , Peter Johannes Servaas Savio VAN EIJK , Mathilda Maria Henrica VERSTAPPEN , Frank L. M. VOS , Eric Jurriën ZIJP , Qiu JUNYING , Rustam Ferdinand GARREY , David Allen SHORT , Angang WANG

IPC分类号： C07D487/04

摘要： The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.

2.

发明公开
PROCESSES FOR THE PREPARATION OF 4-{8-AMINO-3-[(2S)-1-(BUT-2-YNOYL)-PYRROLIDIN-2-YL]IMIDAZO[1,5-a]-PYRAZIN-1-YL}N-(PYRIDIN-2-YL)-BENZAMIDE 审中-公开

公开(公告)号：US20240317766A1

公开(公告)日：2024-09-26

申请号：US18659338

申请日：2024-05-09

申请人： Acerta Pharma B.V.

发明人： Paul Allen BETHEL , Lai Chun CHAN , Katie Grace COOPER , Robert John COX , Michael David GOLDEN , Shaun Alan HUGHES , Lucinda Victoria JACKSON , Kirsty Jane MILLARD , Andrew John PHILLIPS , Alexander James TELFORD , Jerry EVARTS , Michael Joseph LAWLER , Remy E. J. N. LITJENS , Peter Johannes Servaas Savio VAN EIJK , Mathilda Maria Henrica VERSTAPPEN , Frank L. M. VOS , Eric Jurriën ZIJP , Qiu JUNYING , Rustam Ferdinand GARREY , David Allen SHORT , Angang WANG

IPC分类号： C07D487/04 , C07B63/00

CPC分类号： C07D487/04 , C07B63/00 , C07B2200/13

摘要： The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.