专利检索 ap:("Administración General de la Comunidad Autónoma de Euskadi" OR "Universidad Del Pais Vasco/Euskal Herriko Unibersitatea") AND inv:"Sonia Alonso Martin" 第 1 页

1.

发明公开
FOXO INHIBITORS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL PROCESSING OF TDP-43 AND/OR FUS PROTEINS 审中-公开

公开(公告)号：US20240277695A1

公开(公告)日：2024-08-22

申请号：US17928273

申请日：2021-05-27

申请人： Administración General de la Comunidad Autónoma de Euskadi , Universidad Del Pais Vasco/Euskal Herriko Unibersitatea

发明人： Mónica Zufiría García , Gorka Gereñu Lopetegi , Patxi Gil Bea , Sonia Alonso Martin , Jaione Lasa Elgarresta , Adolfo López de Munain Arregui , Jesús María Aizpurua Iparraguirre , José Ignacio Miranda Murua

IPC分类号： A61K31/4709 , A61K31/47 , A61P25/28

CPC分类号： A61K31/4709 , A61K31/47 , A61P25/28

摘要： FoxO inhibitors for use in the treatment of diseases caused by abnormal TDP-43 and/or FUS proteins. The present invention refers to FoxO inhibitors, preferably quinolone derivatives, for use in the treatment of diseases caused by alterations of TDP-43 and/or FUS proteins, preferably Amyotrophic lateral sclerosis (ALS).