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公开(公告)号:US07858785B2
公开(公告)日:2010-12-28
申请号:US12562853
申请日:2009-09-18
申请人: Adrian Leonard Smith , Paul Edward Brennan , Fenel F. Fils , Gang Liu , Nick A. Paras , Daniel Martin Retz , Elizabeth Rainbeau
发明人: Adrian Leonard Smith , Paul Edward Brennan , Fenel F. Fils , Gang Liu , Nick A. Paras , Daniel Martin Retz , Elizabeth Rainbeau
IPC分类号: C07D417/14 , A61K31/506 , A61P19/02 , A61P35/00
CPC分类号: C07D417/14 , C07D409/14
摘要: The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.