公开(公告)号：US10118949B2

公开(公告)日：2018-11-06

申请号：US14551931

申请日：2014-11-24

Applicant: Affibody AB

Inventor： Lars Abrahmsén ,  Andreas Jonsson ,  Jakob Dogan ,  Per-Åke Nygren

IPC: C07K14/00 ,  C07K14/61 ,  C07K14/535 ,  C07K14/755 ,  C07K16/18 ,  C07K14/31 ,  C07K14/315 ,  C07K14/605 ,  A61K38/00

Abstract: The present invention relates to a class of engineered polypeptides having a binding affinity for albumin. It also relates to new methods and uses that exploit binding by these and other compounds to albumin in different contexts, some of which have significance for the treatment of disease in mammals including humans.

公开(公告)号：US20150158916A1

公开(公告)日：2015-06-11

申请号：US14551931

申请日：2014-11-24

Applicant: Affibody AB

Inventor： Lars Abrahmsén ,  Andreas Jonsson ,  Jakob Dogan ,  Per-Åke Nygren

IPC: C07K14/00 ,  C07K16/18 ,  C07K14/535 ,  C07K14/755 ,  C07K14/605 ,  C07K14/61

CPC classification number: C07K14/00 ,  A61K38/00 ,  C07K14/31 ,  C07K14/315 ,  C07K14/535 ,  C07K14/605 ,  C07K14/61 ,  C07K14/755 ,  C07K16/18 ,  C07K2319/00 ,  C07K2319/70

Abstract: The present invention relates to a class of engineered polypeptides having a binding affinity for albumin. It also relates to new methods and uses that exploit binding by these and other compounds to albumin in different contexts, some of which have significance for the treatment of disease in mammals including humans.

Abstract translation: 本发明涉及一类对白蛋白具有结合亲和性的工程化多肽。 它还涉及利用这些和其它化合物在不同背景下结合白蛋白的新方法和用途，其中一些对于包括人在内的哺乳动物的疾病的治疗具有重要意义。