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公开(公告)号：US20130230221A1
公开(公告)日：2013-09-05
申请号：US13689027
申请日：2012-11-29
申请人： AFFYMETRIX, INC.
发明人： Benjamin M. Bolstad , Harry Zuzan
IPC分类号： G06T7/00
摘要： Disclosed are methods and software for biological data analysis. Specifically, provided are methods, computer programs and systems for analyzing data in the form of various intensity measurements obtained from an oligonucleotides microarray experiment. Such data may be microarray data obtained from an experiment conducted to determine copy number of a human genetic sample. The data are corrected by application of one or more covariate adjusters which may be applied simultaneously and which may be selected by a user. Further, the present application provides methods of filtering image data and signal restoration of image data using log2 ratio data.
摘要翻译： 公开了生物数据分析的方法和软件。 具体地，提供了用于分析从寡核苷酸微阵列实验获得的各种强度测量形式的数据的方法，计算机程序和系统。 这样的数据可以是从进行以确定人类遗传样品的拷贝数的实验获得的微阵列数据。 通过应用可以同时应用并且可由用户选择的一个或多个协变量调整器来校正数据。 此外，本申请提供了使用log2比率数据来过滤图像数据和图像数据的信号恢复的方法。
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公开(公告)号：US20200167916A1
公开(公告)日：2020-05-28
申请号：US16669261
申请日：2019-10-30
申请人： Affymetrix, Inc.
发明人： Benjamin M. Bolstad , Harry Zuzan
摘要： Disclosed are methods and software for biological data analysis. Specifically, provided are methods, computer programs and systems for analyzing data in the form of various intensity measurements obtained from an oligonucleotides microarray experiment. Such data may be microarray data obtained from an experiment conducted to determine copy number of a human genetic sample. The data are corrected by application of one or more covariate adjusters which may be applied simultaneously and which may be selected by a user. Further, the present application provides methods of filtering image data and signal restoration of image data using log2 ratio data.
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公开(公告)号：US10515447B2
公开(公告)日：2019-12-24
申请号：US13689027
申请日：2012-11-29
申请人： Affymetrix, Inc.
发明人： Benjamin M. Bolstad , Harry Zuzan
摘要： Disclosed are methods and software for biological data analysis. Specifically, provided are methods, computer programs and systems for analyzing data in the form of various intensity measurements obtained from an oligonucleotides microarray experiment. Such data may be microarray data obtained from an experiment conducted to determine copy number of a human genetic sample. The data are corrected by application of one or more covariate adjusters which may be applied simultaneously and which may be selected by a user. Further, the present application provides methods of filtering image data and signal restoration of image data using log2 ratio data.
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