公开(公告)号：US20230184762A1

公开(公告)日：2023-06-15

申请号：US17596950

申请日：2020-06-26

Applicant: Agency for Science, Technology and Research

Inventor： Florent Ginhoux ,  Charles Antoine Dutertre

IPC: G01N33/569

CPC classification number: G01N33/56972 ,  G01N2333/70596 ,  G01N2800/7095

Abstract: There is provided a method of identifying pro-inflammatory dendritic cells, the method comprising: determining an expression of CD5, CD14 and/or CD163 in cells, wherein CD5−, CD14+ and/or GD163+ cells are identified as pro-inflammatory dendritic cells. Also disclosed is a method of characterising inflammation and/or inflammatory disease in a subject, the method comprising: determining a proportion of CD5−, CD14+ and/or GD163+ dendritic cells in the subject's sample, wherein the proportion positively correlates with the level of inflammation and/or the severity of inflammatory disease in the subject.