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公开(公告)号：US20220340684A1
公开(公告)日：2022-10-27
申请号：US17296184
申请日：2019-11-21
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-I Wang , Patricia Ng , John Connolly , Chia Yin Lee
Abstract: Fc regions comprising modification to increase the affinity of association between the Fc region and TRIM21 are disclosed. Also disclosed are constituent polypeptides of such Fc regions, antigen-binding molecules and immunogens comprising such Fc regions, and nucleic acids encoding and methods using such Fc regions, antigen-binding molecules and immunogens.
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