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1.
公开(公告)号:US09334500B2
公开(公告)日:2016-05-10
申请号:US14348365
申请日:2012-09-28
Applicant: Agency for Science, Technology and Research
Inventor: Qiang Yu , Shuet Theng Lee
IPC: C12N15/11 , C12N15/113 , A61K31/517 , A61K31/713 , A61K45/06 , A61K31/47 , A61K31/4709 , A61K31/5377 , A61K31/519 , A61K31/7088 , C12Q1/68
CPC classification number: C12N15/1135 , A61K31/47 , A61K31/4709 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/7088 , A61K31/713 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2320/31 , C12Q1/6881 , C12Q2600/106 , A61K2300/00
Abstract: A method of treating cancer by inhibiting expression of ubiquitin associated and SH3 domain containing B (UBASH3B) gene or by inhibiting the activity of UBASH3B protein or a functional variant thereof.
Abstract translation: 通过抑制泛素相关和含有B(UBASH3B)基因的SH3结构域的表达或通过抑制UBASH3B蛋白或其功能变体的活性来治疗癌症的方法。
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2.
公开(公告)号:US20140335106A1
公开(公告)日:2014-11-13
申请号:US14348365
申请日:2012-09-28
Applicant: Agency for Science, Technology and Research
Inventor: Qiang Yu , Shuet Theng Lee
IPC: C12N15/113 , A61K45/06 , A61K31/517 , C12Q1/68 , A61K31/519 , A61K31/47 , A61K31/4709 , A61K31/7088 , A61K31/5377
CPC classification number: C12N15/1135 , A61K31/47 , A61K31/4709 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/7088 , A61K31/713 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2320/31 , C12Q1/6881 , C12Q2600/106 , A61K2300/00
Abstract: A method of treating cancer by inhibiting expression of ubiquitin associated and SH3 domain containing B (UBASH3B) gene or by inhibiting the activity of UBASH3B protein or a functional variant thereof.
Abstract translation: 通过抑制泛素相关和含有B(UBASH3B)基因的SH3结构域的表达或通过抑制UBASH3B蛋白或其功能变体的活性来治疗癌症的方法。
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