公开(公告)号：US20240337650A1

公开(公告)日：2024-10-10

申请号：US18574424

申请日：2022-06-27

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Xinting Zheng ,  Laura Sutarlie ,  Yong Yu ,  Xiaodi Su

IPC: G01N33/52 ,  G01N33/53 ,  G01N33/84

CPC classification number: G01N33/523 ,  G01N33/5308 ,  G01N33/84 ,  G01N2800/202

Abstract: There is provided herein a paper-based sensor for simultaneously determining a plurality of biomarkers present in a biological sample comprising a plurality of detection zones in fluid communication with a sampling zone, wherein said plurality of detection zones comprises sensing material specific to each of said plurality of biomarkers. There is also provided herein a method of manufacturing the paper-based sensor, a use of a paper-based sensor for wound diagnosis, a kit comprising the paper-based sensor and a method of diagnosing wound health.

公开(公告)号：US10982138B2

公开(公告)日：2021-04-20

申请号：US15836784

申请日：2017-12-08

Applicant: Agency for Science, Technology and Research

Inventor： Yong Yu ,  Yen Nee Tan

IPC: C09K11/58 ,  C09K11/06

Abstract: The present invention relates to a method for forming a nanocomposite having a core-shell structure, the method comprising the steps of: forming a core comprising a first fluorophore capable of aggregation induced emission, and depositing a second fluorophore capable of aggregation caused quenching onto the surface of the core to form a shell at least partially surrounding the core. The present invention also relates to a nanocomposite obtained by said method, and a method of altering the fluorescence of said nanocomposite. The nanocomposite may exhibit dual emission colours and opposite aggregation fluorescent behaviours.