公开(公告)号：US20130245119A1

公开(公告)日：2013-09-19

申请号：US13885826

申请日：2011-11-18

申请人： Akiko Harauma ,  Fuminori Kawabata ,  Toru Moriguchi ,  Tetsuya Kawakita ,  Kazuo Tsubota

发明人： Akiko Harauma ,  Fuminori Kawabata ,  Toru Moriguchi ,  Tetsuya Kawakita ,  Kazuo Tsubota

IPC分类号： A61K31/202

CPC分类号： A61K31/202 ,  A61K9/0053 ,  A61K31/20 ,  A61K31/232 ,  A61K31/661 ,  A61K35/60 ,  A61K35/612

摘要： The present invention provides an effective and safe prophylactic and therapeutic pharmaceutical agent and supplement for corneal epithelium disorders and/or conjunctival epithelial disorders. This is a therapeutic and/or prophylactic agent for corneal epithelium disorders and/or conjunctival epithelial disorders comprising eicosapentaenoic acid and/or docosahexaenoic acid, a glycerin ester or phospholipid comprising these fatty acids as constituent fatty acids, or a lower alcohol ester of these fatty acids as active ingredients. These preferably comprise EPA and/or DHA in the form of a refined fish oil or refined krill oil. A total of at least approximately 50 to 5,000 mg of EPA and/or DHA or the esters thereof are taken daily, thereby easing corneal epithelium disorders and/or conjunctival epithelial disorders. In addition, the amount of tears may be recovered.

摘要翻译： 本发明提供了一种有效和安全的预防和治疗药剂以及角膜上皮病和/或结膜上皮疾病的补充剂。 这是包含二十碳五烯酸和/或二十二碳六烯酸的角膜上皮细胞病和/或结膜上皮病症的治疗和/或预防剂，包含这些脂肪酸作为构成脂肪酸的甘油酯或磷脂，或这些脂肪酸的低级醇酯 酸作为活性成分。 这些优选包含精制鱼油或精制磷虾油形式的EPA和/或DHA。 每天服用至少约50至5,000mg的EPA和/或DHA或其酯，从而缓解角膜上皮病和/或结膜上皮病。 此外，眼泪量可以恢复。