公开(公告)号：US20240254227A1

公开(公告)日：2024-08-01

申请号：US18637960

申请日：2024-04-17

Applicant: Alector LLC

Inventor： Sarah Emily Headland ,  Ilaria Tassi ,  Chenyu A. Lee ,  Earl Kim ,  Adiljan Ibrahim ,  Marina Roell ,  Angie Grace Yee

IPC: C07K16/28 ,  A61K39/00

CPC classification number: C07K16/2803 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/92

Abstract: The present disclosure is generally directed to antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a CD300LB polypeptide, e.g., a mammalian CD300LB or human CD300LB, and use of such compositions in preventing, reducing risk, or treating a disease or disorder an individual in need thereof.