公开(公告)号：US08992854B2

公开(公告)日：2015-03-31

申请号：US13896782

申请日：2013-05-17

申请人： Alere Switzerland GmbH

发明人： Barry Sinclair Brewster ,  Adrian Leslie Walker ,  Robert John Davies

IPC分类号： G01N33/00 ,  G01N33/543 ,  G01N33/558

CPC分类号： G01N33/54306 ,  G01N33/54386 ,  G01N33/558

摘要： Disclosed is an assay device comprising liquid transport means adapted to take up a liquid sample and conduct the liquid to an analyte detection region operable to provide a test signal indicative of the presence and/or amount of an analyte in the liquid sample; the assay device further comprising a sample presence signal generation means, which is not generated by means of an immunoreaction. This sample presence signal generation means can comprise a colored portion, which is overlaid by a material (e.g. nitrocellulose) that is opaque, when dry, and translucent or transparent, when wet, to allow the colored portion to become visible to the user. In another embodiment the signal generation means comprises a color changing material which under-goes a change in its visible properties upon wetting (e.g. pH indication). A third embodiment uses a mobilizable detectable which, when wetted by the sample, is carried along resulting in a streaked line parallel with the flow direction.

摘要翻译： 公开了一种测定装置，其包括液体输送装置，其适于吸收液体样品并将液体导入分析物检测区域，该区域可操作以提供指示液体样品中分析物的存在和/或量的测试信号; 所述测定装置还包括不是通过免疫反应产生的样品存在信号产生装置。 该样品存在信号产生装置可以包括着色部分，其在被湿润时被干燥，半透明或透明的材料（例如硝酸纤维素）覆盖，以使得着色部分变得对使用者可见。 在另一个实施方案中，信号产生装置包括颜色变化材料，其在润湿（例如pH指示）时其可见性质发生变化。 第三实施例使用可移动的可检测的，当被样品润湿时，被携带，导致与流动方向平行的条纹线。

公开(公告)号：US20140093427A1

公开(公告)日：2014-04-03

申请号：US13896782

申请日：2013-05-17

申请人： Alere Switzerland GmbH

发明人： Barry Sinclair Brewster ,  Adrian Leslie Walker ,  Robert John Davies

IPC分类号： G01N33/543

CPC分类号： G01N33/54306 ,  G01N33/54386 ,  G01N33/558

摘要： Disclosed is an assay device comprising liquid transport means adapted to take up a liquid sample and conduct the liquid to an analyte detection region operable to provide a test signal indicative of the presence and/or amount of an analyte in the liquid sample; the assay device further comprising a sample presence signal generation means, which is not generated by means of immunoreaction. This sample presence signal generation means can comprise a coloured portion, which is overlaid by a material (e.g. nitrocellulose) that is opaque, when dry, and translucent or transparent, when wet, to allow the coloured portion to become visible to the user. In another embodiment the signal generation means comprises a colour changing material which under-goes a change in its visible properties upon wetting (eg. pH indication). A third embodiment uses a mobilisable detectable which, when wetted by the sample, is carried along resulting in a streaked line parallel with the flow direction.

摘要翻译： 公开了一种测定装置，其包括适于吸收液体样品并将液体导入分析物检测区域的液体输送装置，该分析物检测区域可操作以提供指示液体样品中分析物的存在和/或量的测试信号; 测定装置还包括不是通过免疫反应产生的样品存在信号产生装置。 该样品存在信号产生装置可以包括着色部分，其在被湿润时被干燥，半透明或透明的材料（例如硝酸纤维素）覆盖，以使得着色部分变得对使用者可见。 在另一个实施方案中，信号产生装置包括颜色变化材料，其在润湿时（例如，pH指示）会持续变化其可见性质。 第三实施例使用可运动的可检测的，当由样品润湿时，其被携带，导致与流动方向平行的条纹线。