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公开(公告)号:US20170121421A1
公开(公告)日:2017-05-04
申请号:US15333285
申请日:2016-10-25
申请人: Alex CORTEZ , Bernhard Hubert GEIERSTANGER , Timothy Z. HOFFMAN , Shailaja KASIBHATLA , Tetsuo UNO , Xing WANG , Tom Yao-Hsiang WU
发明人: Alex CORTEZ , Bernhard Hubert GEIERSTANGER , Timothy Z. HOFFMAN , Shailaja KASIBHATLA , Tetsuo UNO , Xing WANG , Tom Yao-Hsiang WU
IPC分类号: C07K16/32 , C07K16/28 , C07H15/26 , A61K47/48 , C07D487/04
摘要: Provided herein are antibody conjugates comprising toll-like receptor agonists and the use of such conjugates for the treatment of cancer. In some embodiments, the conjugates comprise anti-HER2 antibodies.