公开(公告)号：US06184397B2

公开(公告)日：2001-02-06

申请号：US09336773

申请日：1999-06-21

申请人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer ,  John D. Higgins, III

发明人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer ,  John D. Higgins, III

IPC分类号： C07J900

CPC分类号： C07J9/00

摘要： The present invention provides a method for the direct esterification of stanols and sterols with catalyst, which can be acidic or basic, in the presence of a color deactivating agent to form stanol/sterol-esters. The method provides a synthetic route that is amenable to large scale production of the esters in high yields. A preferred embodiment employs a food grade process free of organic solvents or mineral acids.

摘要翻译： 本发明提供了一种在颜色减活化剂存在下，使用可以是酸性或碱性的催化剂直接酯化甾烷醇和甾醇以形成甾烷醇/甾醇酯的方法。 该方法提供了一种合成路线，可以高产率大规模生产酯。 优选的实施方案采用不含有机溶剂或无机酸的食品级方法。

公开(公告)号：US06635774B2

公开(公告)日：2003-10-21

申请号：US10139760

申请日：2002-05-06

申请人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer

发明人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer

IPC分类号： C07J900

CPC分类号： C07J9/00

摘要： The present invention provides a method for the direct esterification of stanols and sterols with fatty acids to form stanol/sterol-esters. The method provides a synthetic route that is amenable to large scale production of the esters in high yields. A preferred embodiment employs a food grade process free of organic solvents or mineral acids, does not produce or use non-food grade products and is substantially free of the use of a catalyst.

公开(公告)号：US06410758B1

公开(公告)日：2002-06-25

申请号：US09317712

申请日：1999-05-24

申请人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer

发明人： Allan Roden ,  James L. Williams ,  Ruey Bruce ,  Frank Detrano ,  Marie H. Boyer

IPC分类号： C07J900

摘要： The present invention provides a method for the direct esterification of stanols and sterols with fatty acids to form stanol/sterol-esters. The method provides a synthetic route that is amenable to large scale production of the esters in high yields. A preferred embodiment employs a food grade process free of organic solvents or mineral acids, does not produce or use non-food grade products and is substantially free of the use of a catalyst.