公开(公告)号：US20230190636A1

公开(公告)日：2023-06-22

申请号：US17865020

申请日：2022-07-14

Applicant: Allergan, Inc.

Inventor： Lance Steward ,  Amy Brideau-Andersen ,  Jie Shen ,  Lydia Andrews-Jones ,  Hsiang Ho ,  Betsy Bloom ,  Guang Wei Lu ,  Fangjing Wang ,  Sunny Kumar ,  Gregory Nicholson ,  Ron Broide

IPC: A61K9/00 ,  A61K8/18 ,  A61K38/48 ,  A61Q19/08

CPC classification number: A61K9/0014 ,  A61K8/18 ,  A61K38/4893 ,  A61Q19/08 ,  A61K2800/74 ,  A61Q19/007

Abstract: Methods for delivery of a biologic agent to the dermis or superficial muscles by topical application of the agent are provided. The methods comprise, in one embodiment, treating or conditioning a skin area to disrupt the stratum corneum in the skin area to define a treated skin area and applying a formulation comprising a biologic agent to the treated skin area.

公开(公告)号：US20240226251A1

公开(公告)日：2024-07-11

申请号：US17870093

申请日：2022-07-21

Applicant: Allergan, Inc.

Inventor： James Oliver Dolly ,  Tomas Zurawski ,  Ron Broide ,  Amy Brideau-Andersen ,  James Cunningham ,  Gregory Nicholson

IPC: A61K38/48 ,  A61K45/06 ,  A61K47/18 ,  C12N9/64

CPC classification number: A61K38/4893 ,  A61K45/06 ,  A61K47/18 ,  C12N9/6489 ,  C12Y304/24069

Abstract: Formulations, methods, and kits comprising at least one Clostridium toxin derivative and at least one chemical depolarizing agent suitable for inducing local, partial or complete muscle paralysis or muscle denervation in a subject are described.

公开(公告)号：US20220096609A1

公开(公告)日：2022-03-31

申请号：US17429237

申请日：2020-02-05

Applicant: Allergan, Inc.

Inventor： James Oliver Dolly ,  Tomas Zurawski ,  Ron Broide ,  Amy Brideau-Andersen ,  James Cunningham ,  Gregory Nicholson

IPC: A61K38/48 ,  A61K47/18 ,  A61K45/06 ,  C12N9/64

Abstract: Formulations, methods, and kits comprising at least one Clostridium toxin derivative and at least one chemical depolarizing agent suitable for inducing local, partial or complete muscle paralysis or muscle denervation in a subject are described.