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公开(公告)号:US20200261503A1
公开(公告)日:2020-08-20
申请号:US16695894
申请日:2019-11-26
Applicant: Allogene Therapeutics, Inc.
Inventor: David Chang , Arun Balakumaran , Cyril Alkis Konto
IPC: A61K35/17 , A61P35/00 , A61K47/66 , C07K14/705
Abstract: Provided herein are BCMA CARs and CAR-T cells, methods of making, and using the same. In some embodiments, particular dosing regimens, redosing regimens, and combination regimens with lymphodepletion are provided, for the treatment and clinical management of multiple myeloma in subjects in need thereof.