公开(公告)号：US20170189409A1

公开(公告)日：2017-07-06

申请号：US15313722

申请日：2015-05-21

Applicant: Almirall, S.A.

Inventor： Nuria GODESSART MARINA ,  Cristina BALAGUE PELAEZ

IPC: A61K31/53 ,  C07D487/04

CPC classification number: A61K31/53 ,  A61K31/573 ,  A61K45/06 ,  C07B2200/13 ,  C07C309/04 ,  C07C309/30 ,  C07C309/35 ,  C07D487/04

Abstract: The present invention provides a compound, which is an inhibitor of phosphoinositide 3-kinase delta or a pharmaceutically acceptable salt and/or solvate thereof, for use in the treatment of an immunobullous skin disease mediated by autoantibodies by oral administration.

公开(公告)号：US20230390276A1

公开(公告)日：2023-12-07

申请号：US18249224

申请日：2021-10-15

Applicant: Aslan Pharmaceuticals Pte. Ltd. ,  ALMIRALL, S.A.

Inventor： Robert MOORE ,  Isana ENDO ,  Carl FIRTH ,  Stephen DOYLE ,  Nuria GODESSART MARINA

IPC: A61K31/455 ,  A61K45/06 ,  A61P37/00 ,  A61P19/02 ,  A61P25/02

CPC classification number: A61K31/455 ,  A61K45/06 ,  A61P37/00 ,  A61P19/02 ,  A61P25/02

Abstract: A method of treating an autoimmune disease in a patient comprising administering a therapeutically effective amount of a DHODH inhibitor or a pharmaceutically acceptable salt thereof. Also provided are formulations or compositions suitable for treating autoimmune diseases.

公开(公告)号：US20170151264A1

公开(公告)日：2017-06-01

申请号：US15313737

申请日：2015-05-21

Applicant: Almirall, S.A.

Inventor： Nuria GODESSART MARINA ,  Cristina BALAGUE PELAEZ

IPC: A61K31/573 ,  A61K45/06 ,  A61K31/53

CPC classification number: A61K31/53 ,  A61K31/573 ,  A61K45/06 ,  C07B2200/13 ,  C07C309/04 ,  C07C309/30 ,  C07C309/35 ,  C07D487/04

Abstract: The present invention provides a pharmaceutical composition which comprises (a) a compound which is an inhibitor of phosphoinositide 3-kinase delta or a pharmaceutically acceptable salt and/or solvate thereof, and (b) a corticosteroid.