专利检索 ap:("Alto Neuroscience, Inc.") AND inv:"Josh JORDAN" 第 1 页

1.

发明公开
EFFECTIVE TREATMENT OF DEPRESSION IN PATIENTS HAVING IMPAIRED LEARNING AND/OR MEMORY OR CERTAIN EEG CHARACTERISTICS WITH A BENZYLPIPERAZINE-AMINOPYRIDINE AGENT 审中-公开

公开(公告)号：US20240197721A1

公开(公告)日：2024-06-20

申请号：US18528486

申请日：2023-12-04

申请人： Alto Neuroscience, Inc.

发明人： Amit ETKIN , Wei WU , Chao WANG , Nicholas COOPER , Josh JORDAN , Adam SAVITZ

IPC分类号： A61K31/496 , A61B5/16 , A61B5/372 , A61K9/00 , A61K45/06 , A61P25/24

CPC分类号： A61K31/496 , A61B5/165 , A61B5/372 , A61K9/0053 , A61K45/06 , A61P25/24

摘要： This invention relates to the use of (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone (NSI-189) or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), bipolar disorder, post-traumatic stress disorder, substance use disorder, and depression-related aspects of schizophrenia (e.g. negative symptoms) in select patients who exhibit impaired learning and/or memory. The invention also relates to the use of NSI-189 or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), in select patients who exhibit impaired learning and/or memory or certain EEG characteristics.