公开(公告)号：US20250064064A1

公开(公告)日：2025-02-27

申请号：US18719164

申请日：2022-12-12

Applicant: Amgen Inc.

Inventor： Evan Kruchowy ,  Sai Chakradhar Padala ,  Daniel Marsiglio

IPC: A01N59/00 ,  A01P1/00 ,  A61L2/20 ,  A61L101/02

Abstract: A method for decontaminating a chamber interior using a VPHP decontamination cycle includes sealing the chamber interior, circulating a dose of gas in the chamber interior for a dwell time, and aerating the chamber interior until no more than an allowable remaining amount of the gas remains in the chamber interior. A method for selecting parameters for a VPHP decontamination cycle for a chamber interior includes performing a plurality of experiments testing different amounts of gas and different amounts of time, selecting a dose of the gas to be a least amount of gas that maintains full saturation of the chamber interior over a selected time, and selecting a dwell time such that the dwell time is both less than or equal to the selected time and a least amount of time for which, after circulating the dose of the gas, the remaining amount of viable spores is allowable.