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公开(公告)号：US20180298105A1
公开(公告)日：2018-10-18
申请号：US15907002
申请日：2018-02-27
Applicant: Novo Nordisk A/S , Amgen Inc.
Inventor： Mette D. Andersen , Jeff Dantzler , Richard J. Armitage , Rutillio Clark
IPC: C07K16/28 , C07K14/705 , A61K39/00
Abstract: Provided are compositions and methods relating to human CD30L antigen binding proteins. Compositions described herein include: human CD30L antigen binding proteins, polynucleotides encoding human CD30L antigen binding proteins, vectors comprising these polynucleotides, host cells, and pharmaceutical compositions. Methods of making and using each of these compositions are also provided.
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Patent Agency Ranking
公开(公告)号：US09243058B2
公开(公告)日：2016-01-26
申请号：US14098275
申请日：2013-12-05
Applicant: Amgen Inc.
Inventor： Richard J. Armitage , Michelle Blake , William C. Fanslow, III , Jason Charles O'Neill , Gunasekaran Kannan , Jiangchun Xu , Mark Edward Tometsko
CPC classification number: A61K39/3955 , A61K31/395 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K2039/505 , A61K2039/572 , C07K16/18 , C07K16/2878 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to BCMA antibody drug conjugates.
Abstract translation: 本发明涉及BCMA（B细胞成熟抗原）抗原结合蛋白，例如抗体，编码所述抗原结合蛋白的多核苷酸序列，以及用于诊断和治疗疾病的组合物和方法。 本发明还涉及BCMA抗体药物偶联物。
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公开(公告)号：US10220090B2
公开(公告)日：2019-03-05
申请号：US14967167
申请日：2015-12-11
Applicant: Amgen Inc.
Inventor： Richard J. Armitage , Michelle Blake , William C. Fanslow, III , Jason Charles O'Neill , Gunasekaran Kannan , Jiangchun Xu , Mark Edward Tometsko
IPC: C07K16/18 , A61K45/06 , A61K39/00 , C07K16/28 , A61K39/395 , A61K31/395 , A61K47/68
Abstract: The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to BCMA antibody drug conjugates.
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公开(公告)号：US09926373B2
公开(公告)日：2018-03-27
申请号：US14396248
申请日：2013-04-25
Applicant: Novo Nordisk A/S , Amgen Inc.
Inventor： Mette D. Andersen , Jeff Dantzler , Richard J. Armitage , Rutilio Clark
IPC: A61K38/00 , C07K16/28 , C07K14/705 , A61K39/00
CPC classification number: C07K16/2875 , A61K2039/505 , C07K14/70575 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2319/21 , C07K2319/43 , C07K2319/50
Abstract: Provided are compositions and methods relating to human CD30L antigen binding proteins. Compositions described herein include: human CD30L antigen binding proteins, polynucleotides encoding human CD30L antigen binding proteins, vectors comprising these polynucleotides, host cells, and pharmaceutical compositions. Methods of making and using each of these compositions are also provided.
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公开(公告)号：US20160039940A1
公开(公告)日：2016-02-11
申请号：US14396248
申请日：2013-04-25
Applicant: Novo Nordisk A/S , Amgen Inc.
Inventor： Mette D. Andersen , Jeff Dantzler , Richard J. Armitage , Rutilio Clark
IPC: C07K16/28
CPC classification number: C07K16/2875 , A61K2039/505 , C07K14/70575 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2319/21 , C07K2319/43 , C07K2319/50
Abstract: Provided are compositions and methods relating to human CD30L antigen binding proteins. Compositions described herein include: human CD30L antigen binding proteins, polynucleotides encoding human CD30L antigen binding proteins, vectors comprising these polynucleotides, host cells, and pharmaceutical compositions. Methods of making and using each of these compositions are also provided.
Abstract translation: 提供与人CD30L抗原结合蛋白有关的组合物和方法。 本文描述的组合物包括：人CD30L抗原结合蛋白，编码人CD30L抗原结合蛋白的多核苷酸，包含这些多核苷酸的载体，宿主细胞和药物组合物。 还提供了制备和使用这些组合物的方法。
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公开(公告)号：US10465009B2
公开(公告)日：2019-11-05
申请号：US14649469
申请日：2013-12-05
Applicant: Amgen Inc.
Inventor： Richard J. Armitage , Michelle Blake , William C. Fanslow, III , Jason Charles O'Neill , Gunasekaran Kannan , Jiangchun Xu , Mark Edward Tometsko , Zhulun Wang , Athena Sudom
Abstract: The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to BCMA antibody drug conjugates and uses thereof.
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