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公开(公告)号:US07700572B2
公开(公告)日:2010-04-20
申请号:US10494333
申请日:2002-10-31
申请人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Apfel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
发明人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Apfel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
CPC分类号: C12N15/113 , A61K38/00 , A61K2039/505 , C12N2310/14 , C12N2310/315 , C12N2310/53
摘要: The present invention relates to the use of a specific inhibitor of Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system. Furthermore, methods for preventing, ameliorating and/or treating such diseases are disclosed.
摘要翻译: 本发明涉及Smad7表达或功能的特异性抑制剂在制备用于预防,改善或治疗中枢神经系统疾病和/或所述疾病相关和/或引起的疾病的药物组合物中的用途 的中枢神经系统。 此外,公开了用于预防,改善和/或治疗这些疾病的方法。
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公开(公告)号:US20110207795A1
公开(公告)日:2011-08-25
申请号:US12565629
申请日:2009-09-23
申请人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Apfel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
发明人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Apfel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
IPC分类号: A61K31/7088 , A61P25/00
CPC分类号: C12N15/113 , A61K38/00 , A61K2039/505 , C12N2310/14 , C12N2310/315 , C12N2310/53
摘要: The present invention relates to the use of a specific inhibitor of Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system. Furthermore, methods for preventing, ameliorating and/or treating such diseases are disclosed.
摘要翻译: 本发明涉及Smad7表达或功能的特异性抑制剂在制备用于预防,改善或治疗中枢神经系统疾病和/或所述疾病相关和/或引起的疾病的药物组合物中的用途 的中枢神经系统。 此外,公开了用于预防,改善和/或治疗这些疾病的方法。
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公开(公告)号:US20050119203A1
公开(公告)日:2005-06-02
申请号:US10494333
申请日:2002-10-31
申请人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Appel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
发明人: Andreas Steinbrecher , Gerhard Giegerich , Ingo Kleiter , Markus Horn , Rainer Appel , Roland Kreutzer , Stefan Limmer , Hans-Peter Vornlocher
IPC分类号: A61K38/00 , C12N15/113 , A61K48/00
CPC分类号: C12N15/113 , A61K38/00 , A61K2039/505 , C12N2310/14 , C12N2310/315 , C12N2310/53
摘要: The present invention relates to the use of a specific inhibitor of Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system. Furthermore, methods for preventing, ameliorating and/or treating such diseases are disclosed.
摘要翻译: 本发明涉及Smad7表达或功能的特异性抑制剂在制备用于预防,改善或治疗中枢神经系统疾病和/或所述疾病相关和/或引起的疾病的药物组合物中的用途 的中枢神经系统。 此外,公开了用于预防,改善和/或治疗这些疾病的方法。
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