专利检索 ap:("Andrew Antony Calabrese" OR "David Sebastien Fradet" OR "David Hepworth" OR "Mark Lansdell") AND inv:"David Sebastien Fradet" 第 1 页

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发明授权
(3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists 有权
标题翻译：（3,5-二甲基哌啶-1-基）（4-苯基吡咯烷-3-基）甲酮衍生物作为MCR4激动剂

公开(公告)号：US07649002B2

公开(公告)日：2010-01-19

申请号：US11051144

申请日：2005-02-03

申请人： Andrew Antony Calabrese , David Sebastien Fradet , David Hepworth , Mark Lansdell

发明人： Andrew Antony Calabrese , David Sebastien Fradet , David Hepworth , Mark Lansdell

IPC分类号： A61K31/454 , C07D403/02

CPC分类号： C07D401/06 , C07D401/14 , C07D405/14

摘要： The present invention relates to a class of melanocortin MCR4 agonists of general formula (I) wherein R1, R2, R3, R4 and R5 are as defined herein and especially to selective MCR4 agonist compounds, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

摘要翻译： 本发明涉及一类通式（I）的黑皮质素MCR4激动剂，其中R1，R2，R3，R4和R5如本文所定义，特别是涉及选择性MCR4激动剂化合物在医药中的用途，含有它们的组合物，其制备方法和在这些方法中使用的中间体。