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1.ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS 审中-公开
标题翻译: 作为PKC-THETA抑制剂的异构嘌呤和1H-咪唑吡啶公开(公告)号:US20090281075A1
公开(公告)日:2009-11-12
申请号:US12267271
申请日:2008-11-07
申请人: Andrew L. Roughton , Yajing Rong , Koc-Kan Ho , Michael J. Ohlmeyer , David Diller , Ray Jui-Hsiang Chan , Gaifa Lai
发明人: Andrew L. Roughton , Yajing Rong , Koc-Kan Ho , Michael J. Ohlmeyer , David Diller , Ray Jui-Hsiang Chan , Gaifa Lai
IPC分类号: A61K31/397 , C07D473/18 , A61K31/522 , A61K31/496 , C07D471/02 , A61K31/437 , C07D413/14 , A61K31/5377 , A61P37/06 , A61P29/00 , A61P35/00 , A61P3/10
CPC分类号: C07D473/18 , C07D413/14 , C07D471/04
摘要: A chemical genus of purinones and 1H-imidazopyridinones, which are useful as PKCθ inhibitors, and their methods of use are disclosed. The genus is represented by the formula I:
摘要翻译: 公开了可用作PKCθ抑制剂的嘌呤酮和1H-咪唑并吡啶酮的化学属及其使用方法。 该属由式I表示: