专利检索 ap:("Aranapakam M. VENKATESAN" OR "Christoph DEHNHARDT" OR "Zecheng CHEN" OR "Osvaldo Dos SANTOS" OR "Efren Delos SANTOS" OR "Kevin CURRAN" OR "Semiramis AYRAL-KALOUSTIAN" OR "Lei CHEN") AND inv:"Efren Delos SANTOS" 第 1 页

1.

发明申请
AMINO-SUBSTITUTED QUINAZOLINE DERIVATIVES AS INHIBITORS OF BETA-CATENIN/TCF-4 PATHWAY AND CANCER TREATMENT AGENTS 审中-公开
标题翻译：氨基取代的喹唑啉衍生物作为β-卡培宁/ TCF-4途径和癌症治疗剂的抑制剂

公开(公告)号：US20090004185A1

公开(公告)日：2009-01-01

申请号：US11972237

申请日：2008-01-10

申请人： Aranapakam M. VENKATESAN , Christoph DEHNHARDT , Zecheng CHEN , Osvaldo Dos SANTOS , Efren Delos SANTOS , Kevin CURRAN , Semiramis AYRAL-KALOUSTIAN , Lei CHEN

发明人： Aranapakam M. VENKATESAN , Christoph DEHNHARDT , Zecheng CHEN , Osvaldo Dos SANTOS , Efren Delos SANTOS , Kevin CURRAN , Semiramis AYRAL-KALOUSTIAN , Lei CHEN

IPC分类号： C07D239/95 , A61K31/498 , C07D401/02 , C07D403/02 , C07D413/02 , A61K31/5377 , A61K31/55 , A61K39/395 , A61P35/00

CPC分类号： C07D239/95 , C07D401/12 , C07D401/14 , C07D403/12

摘要： The present invention relates to amino-substituted quinazoline derivatives as inhibitors of β-catenin/tcf-4 pathway, which can be useful in the treatment of cancer; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.

摘要翻译： 本发明涉及作为β-catenin / tcf-4途径抑制剂的氨基取代喹唑啉衍生物，其可用于治疗癌症; 进行准备; 包含它们的药物组合物; 以及使用它们的方法。