公开(公告)号：US20240124490A1

公开(公告)日：2024-04-18

申请号：US18219046

申请日：2023-07-06

申请人： Arcus Biosciences, Inc.

发明人： Joshua R. Corbin ,  Sandeep Dhanju ,  Corinne Nicole Foley ,  Jeremy Fournier ,  Padmanabha V. Kattamuri ,  Manmohan Reddy Leleti ,  Pradeep Nareddy ,  Jay Patrick Powers ,  Ehesan Ul Sharif ,  Joice Thomas

IPC分类号： C07D519/00 ,  C07D513/04

CPC分类号： C07D519/00 ,  C07D513/04

摘要： Disclosed herein are compounds that are Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors having a structure according to Formula I, and compositions containing those compounds. Methods of preparing the compounds, and methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.