公开(公告)号：US06416961B1

公开(公告)日：2002-07-09

申请号：US09381042

申请日：1999-09-14

申请人： Ari Ristimäki ,  Matti Härkönen ,  Pentti Sipponen

发明人： Ari Ristimäki ,  Matti Härkönen ,  Pentti Sipponen

IPC分类号： G01M3353

CPC分类号： C12Q1/6841 ,  C12Q1/6886 ,  C12Q2600/158 ,  G01N33/57446 ,  G01N33/57484

摘要： The present invention pertains to a method for determination of the significance of a histologically detected premalignant lesion as a risk for intestinal type gastric cancer or carcinoma in situ, comprising detecting from a patient sample comprising gastric mucosa cells a) cyclooxygenase-2 Cox-2) mRNA expression, or b) Cox-2 protein; wherein overexpression of Cox-2 is indicative of an increased risk for intestinal type gastric cancer.

摘要翻译： 本发明涉及一种用于确定组织学检测的恶化前病变作为肠型胃癌或原位癌的风险的意义的方法，包括从包含胃粘膜细胞的患者样品检测a）环加氧酶-2 Cox-2）mRNA 表达，orb）Cox-2蛋白;其中Cox-2的过表达指示肠型胃癌的风险增加。

公开(公告)号：US20110044080A1

公开(公告)日：2011-02-24

申请号：US12837682

申请日：2010-07-16

申请人： Ari Ristimäki ,  Nicklas Södö ,  Matti Takala ,  Mika Levonen

发明人： Ari Ristimäki ,  Nicklas Södö ,  Matti Takala ,  Mika Levonen

IPC分类号： H02M7/06 ,  H02H9/04

CPC分类号： H02M1/32

摘要： A converter includes a converter bridge (101) adapted to transfer electrical energy between the AC terminal (102) and the DC terminal (103) of the converter. The converter also includes electrical paths bypassing the converter bridge for conducting overvoltage transients occurring in the AC terminal around the converter bridge to the DC terminal. Each electrical path includes a unidirectionally conductive semiconductor component (104a, 104b, 104c), such as a diode, and a voltage-limiting component (105) for which the ratio of voltage change to current change is small when the voltage of the voltage-limiting component is greater than a predetermined threshold voltage. Because of the overvoltage protection thus achieved, AC chokes can be omitted from the AC terminal or at least they can be designed smaller, reducing the load-dependent voltage drop of the DC terminal.

摘要翻译： A转换器包括适于在AC端子（102）和转换器的DC端子（103）之间传递电能的转换器桥（101）。 转换器还包括绕过转换器桥的电路，用于将转换器桥周围的AC端子中的过电压瞬变发生到DC端。 每个电路包括诸如二极管的单向导电半导体部件（104a，104b，104c）以及当电压 - 电压的电压变化时电压变化与电流变化的比例小的限压部件（105） 限制分量大于预定阈值电压。 由于这样实现了过电压保护，因此可以从AC端子省略AC扼流圈，或者至少可以将其设计得更小，从而减小DC端子的负载相关的电压降。

公开(公告)号：US08670253B2

公开(公告)日：2014-03-11

申请号：US12837682

申请日：2010-07-16

申请人： Ari Ristimäki ,  Nicklas Södö ,  Matti Takala ,  Mika Levonen

发明人： Ari Ristimäki ,  Nicklas Södö ,  Matti Takala ,  Mika Levonen

IPC分类号： H02M1/32 ,  H02M7/155

CPC分类号： H02M1/32

摘要： A converter includes a converter bridge (101) adapted to transfer electrical energy between the AC terminal (102) and the DC terminal (103) of the converter. The converter also includes electrical paths bypassing the converter bridge for conducting overvoltage transients occurring in the AC terminal around the converter bridge to the DC terminal. Each electrical path includes a unidirectionally conductive semiconductor component (104a, 104b, 104c), such as a diode, and a voltage-limiting component (105) for which the ratio of voltage change to current change is small when the voltage of the voltage-limiting component is greater than a predetermined threshold voltage. Because of the overvoltage protection thus achieved, AC chokes can be omitted from the AC terminal or at least they can be designed smaller, reducing the load-dependent voltage drop of the DC terminal.

摘要翻译： A转换器包括适于在AC端子（102）和转换器的DC端子（103）之间传递电能的转换器桥（101）。 转换器还包括绕过转换器桥的电路，用于将转换器桥周围的AC端子中的过电压瞬变发生到DC端。 每个电路包括诸如二极管的单向导电半导体部件（104a，104b，104c）以及当电压 - 电压的电压变化时电压变化与电流变化的比例小的限压部件（105） 限制分量大于预定阈值电压。 由于这样实现了过电压保护，因此可以从AC端子省略AC扼流圈，或者至少可以将其设计得更小，从而减小DC端子的负载相关的电压降。