公开(公告)号：US20170067902A1

公开(公告)日：2017-03-09

申请号：US15119549

申请日：2015-02-18

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Peiming ZHANG ,  Stuart LINDSAY ,  Subhadip SENAPATI ,  Sudipta BISWAS

IPC: G01N33/58 ,  G01Q60/38 ,  C12Q1/68 ,  C07D495/04

CPC classification number: G01N33/587 ,  C07C247/04 ,  C07D495/04 ,  C12Q1/6816 ,  C12Q1/6834 ,  G01N33/58 ,  G01Q60/38 ,  C12Q2563/131

Abstract: Embodiments of the present disclosure provide bisbiotin ligands and related conjugates and methods. The bisbiotin ligands, combined with streptavidin, can be used in the separation, labelling, targeting, and immobilization of biomolecules.

Abstract translation: 本公开的实施方案提供双生物素配体和相关的缀合物和方法。 结合链霉抗生物素蛋白的双生物素配体可用于分离，标记，靶向和固定生物分子。

公开(公告)号：US20170343558A1

公开(公告)日：2017-11-30

申请号：US15672437

申请日：2017-08-09

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Stuart LINDSAY ,  Peiming ZHANG ,  Sudipta BISWAS

IPC: G01N33/68 ,  G01N33/487 ,  C07K1/107

CPC classification number: G01N33/6818 ,  C07K1/107 ,  G01N33/48721

Abstract: Embodiments disclosed herein are directed to recognition tunneling systems, methods and devices, and more particularly, to chemical reactions for selectively labeling proteins and peptides and placing protein and/or peptides into, or onto a nanopore formed in a solid support and threading such in and/or through the nanopore, with such nanopores, in some embodiments, including a molecular motor to pull or otherwise force the protein/peptide through the nanopore.