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公开(公告)号:US20250059168A1
公开(公告)日:2025-02-20
申请号:US18937878
申请日:2024-11-05
Applicant: Arvinas Operations, Inc.
IPC: C07D401/14
Abstract: The present disclosure relates to polymorphic forms of(S)-3-(5-(4-((1-(4-((1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl) phenyl) piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl) piperidine-2,6-dione, methods of making these polymorphic forms, and compositions comprising these polymorphic forms. These polymorphic forms are useful in the treatment of various diseases, including, for example, breast cancer.