公开(公告)号：US20230357271A1

公开(公告)日：2023-11-09

申请号：US18028578

申请日：2020-09-30

申请人： Asahi Kasei Pharma Corporation ,  Vernalis (R&D) Limited

发明人： Takahiko ITO ,  Misato TAKASHIMA ,  Masakazu ATOBE ,  Koichiro ARAI ,  Tomohisa TOYAMA ,  Yu YOSHII ,  Andrew John POTTER ,  Daniel Paul MADDOX ,  Stuart RAY ,  Nicolas FOLOPPE

IPC分类号： C07D498/18

CPC分类号： C07D498/18

摘要： A compound represented by the general formula (1) or a salt thereof, which has a superior IRAK-4 inhibitory activity, and is useful as active ingredients of medicaments for prophylactic treatment and/or therapeutic treatment of diseases relating to IRAK-4 inhibition.

公开(公告)号：US20240025893A1

公开(公告)日：2024-01-25

申请号：US18029289

申请日：2020-09-30

申请人： Asahi Kasei Pharma Corporation ,  Vernalis (R&D) Limited

发明人： Koichiro ARAI ,  Kenichiro TAKABA ,  Masakazu ATOBE ,  Misato TAKASHIMA ,  Naomi AONO ,  Andrew John POTTER ,  Daniel Paul MADDOX

IPC分类号： C07D471/04 ,  C07D417/08 ,  C07D417/14 ,  C07D498/18 ,  C07D491/107 ,  A61P35/02 ,  A61P19/02

CPC分类号： C07D471/04 ,  C07D417/08 ,  C07D417/14 ,  A61P19/02 ,  C07D491/107 ,  A61P35/02 ,  C07D498/18

摘要： A compound represented by the general formula (1) or a salt thereof, which has a superior IRAK-4 inhibitory activity, and is useful as active ingredients of medicaments for prophylactic treatment and/or therapeutic treatment of diseases relating to IRAK-4 inhibition.