专利检索 ap:("Augusta University Research Institute, Inc.") AND inv:"Siva PANDA" 第 1 页

1.

发明公开
PYRAZINOIC ACID CONJUGATES AND HYBRID CONJUGATES 审中-公开

公开(公告)号：US20230159471A1

公开(公告)日：2023-05-25

申请号：US18156316

申请日：2023-01-18

申请人： Augusta University Research Institute, Inc.

发明人： Siva PANDA

IPC分类号： C07D241/24 , C07D401/12 , C07D413/12 , A61P31/06 , C07D401/14

CPC分类号： C07D241/24 , C07D401/12 , C07D413/12 , A61P31/06 , C07D401/14 , A61K9/0053

摘要： Pyrazinamide (PZA) conjugates and hybrids are provided herein. The PZA conjugates are useful for treating bacterial infections. In one embodiment, the PZA conjugates are useful for treating tuberculosis.

2.

发明申请
Synthesis of Ibuprofen Hybrid Conjugates as Anti-Inflammatory and Analgesic Agents 有权

公开(公告)号：US20210361597A1

公开(公告)日：2021-11-25

申请号：US17324258

申请日：2021-05-19

申请人： Augusta University Research Institute, Inc.

发明人： Siva PANDA

IPC分类号： A61K31/165 , A61K47/54 , A61K31/167 , A61P29/00

摘要： Disclosed herein as ibuprofen hybrid conjugates and methods of their use to reduce inflammation, pain, and fever. The ibuprofen conjugates have potent anti-inflammatory and analgesic properties with low potential for ulcerogenic activity. An exemplary compound is an ibuprofen-amino acid-4-aminophenol hybrid. Also disclosed are methods of treating or reducing inflammation, pain, and fever in a subject.