公开(公告)号：US10450261B2

公开(公告)日：2019-10-22

申请号：US15577393

申请日：2016-05-27

Applicant: BASF SE

Inventor： Thomas Schaub ,  Joan Gallardo Donaire ,  Martin Ernst

IPC: C07C209/26 ,  B01J31/18 ,  B01J31/20 ,  B01J31/24 ,  C07C213/02 ,  C07F17/02 ,  B01J31/22 ,  C07D265/30 ,  C07D317/58

Abstract: The present invention relates to a method for the reductive amination of a carbonyl compound, comprising one or more carbonyl groups amenable to reductive amination, forming the corresponding primary amine, characterized in that the reaction is carried out in the presence of a homogeneously dissolved catalyst complex K, comprising at least one metal atom from Group 8, 9 or 10 of the periodic table, bearing a bidentate phosphane ligand, a carbonyl ligand, a neutral ligand and a hydride ligand, and also an acid as co-catalyst.