公开(公告)号：US3911126A

公开(公告)日：1975-10-07

申请号：US46671974

申请日：1974-05-03

Applicant: BAYER AG

Inventor： BOSHAGEN HORST ,  PLEMPEL MANFRED

IPC: C07D241/42 ,  C07D243/12 ,  A61K31/54

CPC classification number: C07D241/42 ,  C07D243/12

Abstract: Pharmaceutical compositions which have utility as antimycotics in the treatment of fungal infections which are pathogenic to humans and animals wherein the active ingredient is an N(aryloxy-thiocarbonyl)-benzothiazine and method of using same.

Abstract translation: 在治疗对人和动物致病的真菌感染中具有抗真菌作用的药物组合物，其中活性成分是N- [芳氧基 - 硫代羰基] - 苯并噻嗪及其使用方法。

公开(公告)号：US3692795A

公开(公告)日：1972-09-19

申请号：US3692795D

申请日：1969-09-12

Applicant: BAYER AG

Inventor： BOSHAGEN HORST

IPC: C07D275/02 ,  C07D275/03 ,  C07D275/04 ,  C07D91/46

CPC classification number: C07D275/03 ,  C07D275/04

Abstract: 3-Amino-isothiazoles and derivatives thereof of the formula: OR A SALT THEREOF, WHEREIN R2 and R3 are the same or different and are hydrogen, unsubstituted or substituted aralkyl, unsubstituted or substituted aryl or an unsubstituted or substituted aliphatic moiety, or R2 and R3 are both alkyl linked together to form an anellated five- to seven-membered unsaturated or saturated, unsubstituted or substituted ring system, X is hydrogen or -CO-R1, and R1 is unsubstituted or substituted aralkyl, unsubstituted or substituted aryl or an unsubstituted or substituted aliphatic moiety, are produced by reacting a compound of the formula: WHEREIN R1, R2, and R3 are as above defined, or a salt thereof, with at least a twice-molar quantity of hydroxylamine in the presence of a water-miscible organic solvent at an elevated temperature, and the N-acylamines thus formed are optionally hydrolyzed, optionally without intermediate isolation. The 3-amino-isothiazoles and derivatives so produced are useful for their fungicidal activity and may be used in treating humans, animals and plants against various fungal infections.

Abstract translation: 3-氨基 - 异噻唑及其衍生物，其分子式如下：

公开(公告)号：US3908005A

公开(公告)日：1975-09-23

申请号：US44958174

申请日：1974-03-08

Applicant: BAYER AG

Inventor： LORENZ WALTER ,  BOSHAGEN HORST ,  HAMMANN INGEBORG ,  BEHRENZ WOLFGANG ,  HOMEYER BERNHARD

IPC: C07F9/653 ,  A01N9/36

CPC classification number: C07F9/65324

Abstract: Benzisoxazolo(thiono)phosphoric(phosphonic)acid esters of the general formula

IN WHICH R is a lower alkyl radial, R1 is a lower alkyl or alkoxy radical, and X is an oxygen or sulfur atom, WHICH POSSESS INSECTICIDAL, ACARICIDAL, NEMATOCIDAL AND, IN SOME CASES, FUNGICIDAL PROPERTIES.

Abstract translation: 苯并异恶唑（thiono）磷酸（膦酸）酯，其通式为：其中R为低级烷基，R1为低级烷基或烷氧基，X为氧或硫原子，其为无毒杀虫剂，杀虫剂，杀虫剂， 在某些情况下，防伪特性。

公开(公告)号：US3914242A

公开(公告)日：1975-10-21

申请号：US78424968

申请日：1968-12-16

Applicant: BAYER AG

Inventor： BOSHAGEN HORST ,  GEIGER WALTER ,  MEDENWALD HANS

IPC: C07D275/04

CPC classification number: C07D275/04

Abstract: 3-IMINO-1,2-BENZISOTHIAZOLINES OF THE FORMULA:

D R A W I N G

Abstract translation: 3-氨基-1,2-BENZISOTHIAZOLINES：（R2）n -R1 PARALLEL NH。

公开(公告)号：US3880847A

公开(公告)日：1975-04-29

申请号：US29248472

申请日：1972-09-27

Applicant: BAYER AG

Inventor： BOSHAGEN HORST ,  PLEMPEL MANFRED

IPC: C07D209/08 ,  C07D241/42 ,  C07D243/12 ,  C07D93/12

CPC classification number: C07D241/42 ,  C07D209/08 ,  C07D243/12

Abstract: Compounds of the formula:

WHEREIN X is sulphur, oxygen, NR1, CO, CHR1 or CR1 wherein R1 is hydrogen or straight branched chain lower alkyl, Y is a straight or branched chain aliphatic moiety of one to three carbon atoms, or said aliphatic moiety linked to X by a double bond, R is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylmercapto or trifluoromethyl, N IS 1, 2 OR 3, AND Ar is an unsubstituted or substituted aromatic moiety, ARE PRODUCED BY REACTING A COMPOUND OF THE FORMULA:

WHEREIN X, Y, R and n are as above defined with a thiocarbonic acid ester halide of the formula:

Abstract translation: 下式的化合物：