公开(公告)号：US6372916B2

公开(公告)日：2002-04-16

申请号：US75058900

申请日：2000-12-28

Applicant: BAYER AG

Inventor： LANTZSCH REINHARD ,  JAUTELAT MANFRED ,  HUPPERTS ACHIM ,  ERDMAN DAVID

IPC: C07D249/12

CPC classification number: C07D249/12

Abstract: According to a novel process, it is possible to prepare triazolinethione derivatives of the formulain which R1 and R2 are each as defined in the description bya) reacting hydrazine derivatives of the formula with carbonyl compounds of the formulain which R3 and R4 are each as defined in the description with potassium thiocyanate, sodium thiocyanate or ammonium thiocyanate,if appropriate in the presence of a diluent and if appropriate in the presence of an acid, andb) reacting the resulting triazolidinethione derivatives of the formula with formic acid, if appropriate in the presence of a catalyst and if appropriate in the presence of a diluent.The triazolidinethione derivatives of the formula (V) are novel.

Abstract translation: 根据新的方法，可以制备式的三唑啉酮衍生物，其中R1和R2各自如说明书中所定义，a）使式的肼衍生物与式的羰基化合物反应，其中R3和R4各自如 如果在稀释剂存在下和适当的情况下在酸存在下，硫氰酸钠，硫氰酸钠或硫氰酸铵的描述，以及b）如果合适的话，在酸的存在下，将所得到的式I的三唑烷硫酮衍生物与甲酸反应， 催化剂，如果合适，则在稀释剂存在下。式（Ⅴ）的三唑烷酮二酮衍生物是新颖的。