公开(公告)号：US3682906A

公开(公告)日：1972-08-08

申请号：US3682906D

申请日：1969-11-28

Applicant: BAYER AG

Inventor： SENG FLORIN ,  LEY KURT ,  METZER KARL GEORG

IPC: A61K20060101 ,  C07D20060101 ,  C07D241/52 ,  C07D491/04 ,  C07D51/78

CPC classification number: C07D241/52 ,  C07D491/04

Abstract: CERTAIN 2-HYDROXYMETHYL-3-CARBOXYLIC ACID AMIDOQUINOXALINE-DI-N-OXIDES(1,4) ARE PROVIDED HAVING ANTIBACTERIAL ACTIVITY AGAINST BOTH GRAM-NEGATIVE AND GRAMPOSITIVE ORGANISMS. THE COMPOUNDS ARE USEFUL ALSO IN ANIMAL FEEDS AND DRINKING WATER AND ARE MADE BY REACTING THE CORRESPONDING LACTONE WITH AMMONIA OR AN AMINE IN A DILUENT AT 0* TO 80*C.