公开(公告)号：US20170354620A1

公开(公告)日：2017-12-14

申请号：US15537280

申请日：2015-12-16

申请人： BAYER PHARMA AKTIENGESELLSCHAFT

发明人： Nico BRÄUER ,  Jens NAGEL ,  Horst IRLBACHER ,  Andrea ROTGERI ,  Wolfgang SCHWEDE ,  Henrik DAHLLÖF ,  Marcus KOPPITZ ,  Michaele PETERS ,  Anne-Marie GODINHO-COELHO

IPC分类号： A61K31/167 ,  C07D213/61 ,  C07D213/56 ,  A61K31/44

CPC分类号： A61K31/167 ,  A61K31/44 ,  C07D213/56 ,  C07D213/61 ,  C07D213/64 ,  C07D213/65 ,  C07D213/84 ,  C07D405/12

摘要： The present invention relates to substituted Pyridyl-cycloalkyl-carboxylic acids of general formula (I), to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular in mammals, such as diseases associated with pains, or for the treatment or prophylaxis of pain syndromes (acute and chronic), inflammatory-induced pain, pelvic pain, cancer-associated pain, endometriosis-associated pain as well as endometriosis and adenomyosis as such, cancer as such, and proliferative diseases as such like endometriosis.