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公开(公告)号：US20180273548A1
公开(公告)日：2018-09-27
申请号：US15764283
申请日：2016-09-26
发明人： Ulrich LÜCKING , Jens GEISLER , Daniel HOG , Arne SCHOLZ , Kirstin PETERSEN , Philip LIENAU , Christian STEGMANN , Dorothee ANDRES , Kunzeng ZHENG , Ping GAO , Gang CHEN , Jiajun XI , Simon Anthony HERBERT , Gerhard SIEMEISTER , Nicolas WERBECK
IPC分类号： C07D498/18 , C07D498/08 , A61P35/00
摘要： The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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公开(公告)号：US20180282346A1
公开(公告)日：2018-10-04
申请号：US15764289
申请日：2016-09-30
发明人： Ulrich LÜCKING , Daniel HOG , Jens GEISLER , Arne SCHOLZ , Kirstin PETERSEN , Philip LIENAU , Christian STEGMANN , Dorothee ANDRES , Gerhard SIEMEISTER , Nicolas WERBECK
IPC分类号： C07D498/18 , A61P35/00 , A61P35/02 , A61K31/439 , A61K31/529 , C07D498/08 , C07C53/06 , C07D515/08
CPC分类号： C07D498/18 , A61K31/439 , A61K31/529 , A61P35/00 , A61P35/02 , C07C53/06 , C07D498/08 , C07D515/08
摘要： The present invention relates to novel modified macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
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