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![N-SUBSTITUTED 8-[(2,6-DIFLUOROBENZYL)OXY]-2,6-DIMETHYLIMIDAZO[1,2-A]PYRAZIN-3-CARBOXAMIDE DERIVATIVES AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE (SGC) FOR THE TREATMENT OF CARDIOVASCULAR DISEASES](/abs-image/US/2018/01/25/US20180022751A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180022751A1
公开(公告)日：2018-01-25
申请号：US15548310
申请日：2016-02-02
发明人： Alexandros VAKALOPOULOS , Damian BROCKSCHNIEDER , Frank WUNDER , Johannes-Peter STASCH , Tobias MARQUARDT , Lisa DIETZ , Min Jian Volkhart LI
IPC分类号： C07D487/04 , A61K45/06 , A61K31/695 , A61K31/4985 , C07B59/00 , C07F7/08
CPC分类号： C07D487/04 , A61K31/4985 , A61K31/695 , A61K45/06 , C07B59/002 , C07B2200/05 , C07F7/0812
摘要： The present application relates to novel substituted imidazo[1,2-a]pyrazine carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
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![Substituted pyrazolo[1,5-a]-pyridine-3-carboxamides and use thereof](/abs-image/US/2018/02/08/US20180037580A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180037580A1
公开(公告)日：2018-02-08
申请号：US15548158
申请日：2016-02-02
发明人： Alexandros VAKALOPOULOS , Damian BROCKSCHNIEDER , Frank WUNDER , Johannes-Peter STASCH , Tobias MARQUARDT , Lisa DIETZ , Min Jian Volkhart LI
IPC分类号： C07D471/04
CPC分类号： C07D471/04
摘要： The present application relates to novel substituted pyrazolo[1,5-a]pyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
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