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1.
公开(公告)号:US20180333418A1
公开(公告)日:2018-11-22
申请号:US15534033
申请日:2015-12-08
发明人: Peter ELLINGHAUS , Melanie HEROULT
IPC分类号: A61K31/53 , C12Q1/6886 , A61K31/506 , A61K31/496 , A61K31/498 , A61K31/4184 , A61P35/00
CPC分类号: A61K31/53 , A61K31/4184 , A61K31/496 , A61K31/4965 , A61K31/498 , A61K31/506 , A61P35/00 , C12Q1/6886 , C12Q2600/106
摘要: The current invention is based on a pan FGFR inhibitor for use in the treatment of cancer in a subject, wherein the subject is one for whom the sum of FGFR1, FGFR2 and/or FGFR3 mRNA in a tumor tissue sample from the subject has been found to be overexpressed.