公开(公告)号：US20180117067A1

公开(公告)日：2018-05-03

申请号：US15563304

申请日：2016-03-30

Applicant: BAYLOR RESEARCH INSTITUTE

Inventor： Mazhar Adnan KANAK ,  Bashoo NAZIRUDDIN ,  Marlon F. Levy

IPC: A61K31/585 ,  A61P1/18

Abstract: It was discovered that NF-κB signaling pathway plays a central role in pancreatitis, and inhibition of NF-κB signaling has the potential to reduce the incidence of pancreatitis and protect pancreatic tissues from inflammatory damage. Aspects of the disclosure relate to a method for inhibiting or treating pancreatitis in a subject in need thereof comprising administering a therapeutically effective amount of an NF-κB signaling pathway inhibitor to the subject.